Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.51 |
| ▸ | LPAR4 | Q99677 | 4/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096998 | 0.96 | USP2 (0.65) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1164492 | 0.96 | USP2 (0.65) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1164493 | 0.96 | USP2 (0.65) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20072294 | 0.91 | USP2 (0.68) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1965555 | 0.91 | USP2 (0.68) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13054629 | 0.91 | USP2 (0.68) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27881284 | 0.91 | USP2 (0.68) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20248050 | 0.84 | USP2 (0.76) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20063077 | 0.84 | USP2 (0.64) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20063072 | 0.84 | USP2 (0.76) | USP2CYP3A4MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281387-A1 | Chemosensory Receptor Ligand-Based Therapies | ELCELYX THERAPEUTICS, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281387-A1 | Chemosensory Receptor Ligand-Based Therapies | ELCELYX THERAPEUTICS, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| WO-2012054528-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281387-A1 | Chemosensory Receptor Ligand-Based Therapies | GPR119, TAS1R2, TAS2R1 | USP2 2583/4885CYP3A4 4748/4885MAPT 4181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.