Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62649 | 1.00 | KMT2A (0.41) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL31368630 | 1.00 | KMT2A (0.41) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL21032131 | 0.90 | KDM4E (0.45) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL11481688 | 0.88 | NPSR1 (0.46) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL61643 | 0.81 | KDM4E (0.40) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL29635248 | 0.81 | KDM4E (0.49) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL10995189 | 0.81 | KDM4E (0.49) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL22712475 | 0.81 | ALDH1A1 (0.46) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL62780 | 0.81 | KDM4E (0.40) | KMT2AKDM4EMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL27192993 | 0.81 | NPSR1 (0.40) | KMT2AKDM4EMEN1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024250984-A1 | ANTIBODY-DRUG CONJUGATE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION THEREFOR AND USE THEREOF | 上海维申医药有限公司 | 2024-12-12 | — | — | WO | disclosed |
| WO-2024250985-A1 | TOLL-LIKE RECEPTOR AGONIST HETEROCYCLIC DERIVATIVE, PREPARATION THEREOF, AND USE THEREOF | 上海维申医药有限公司 | 2024-12-12 | — | — | WO | disclosed |