Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727547 | 0.95 | MDM4 (0.50) | MDM4TP53GPR34MDM2CASP3 | |
| SCHEMBL120479 | 0.95 | MDM4 (0.50) | MDM4TP53GPR34MDM2CASP3 | |
| SCHEMBL119454 | 0.95 | MDM4 (0.50) | MDM4TP53GPR34MDM2CASP3 | |
| SCHEMBL29907902 | 0.95 | MDM4 (0.50) | MDM4TP53GPR34MDM2CASP3 | |
| SCHEMBL29528946 | 0.95 | MDM4 (0.50) | MDM4TP53GPR34MDM2CASP3 | |
| SCHEMBL30686154 | 0.95 | MDM4 (0.50) | MDM4TP53GPR34MDM2CASP3 | |
| SCHEMBL25357411 | 0.93 | MDM4 (0.49) | MDM4TP53MDM2CTSBCTSS | |
| SCHEMBL25357407 | 0.93 | MDM4 (0.49) | MDM4TP53MDM2CTSBCTSS | |
| SCHEMBL31210296 | 0.91 | MDM4 (0.56) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL9170986 | 0.88 | MDM4 (0.56) | MDM4TP53MDM2CASP3SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | MDM4 2155/4885TP53 3262/4885GPR34 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.