SCHEMBL31369781

SCHEMBL31369781

N[C@@H](Cc1cccc(-c2cccc(F)c2)c1)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 1/20 0.71
SLC1A1 P43005 2/20 0.58
SLC7A5 Q01650 4/20 0.57
ALPI P09923 1/20 0.57
PKM P14618 1/20 0.57
PTGS1 P23219 1/20 0.57
XIAP P98170 1/20 0.57
MAPK1 P28482 1/20 0.54
NOS3 P29474 2/20 0.54
NOS1 P29475 2/20 0.54
NOS2 P35228 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Fluorophenylalanine SCHEMBL42949 0.91 SLC1A1 (0.69) GRIA2SLC1A1SLC7A5ALPIPKM
M-Fluorophenylalanine SCHEMBL29424682 0.91 SLC1A1 (0.69) GRIA2SLC1A1SLC7A5ALPIPKM
M-Fluorophenylalanine SCHEMBL42948 0.91 SLC1A1 (0.69) GRIA2SLC1A1SLC7A5ALPIPKM
M-Fluorophenylalanine SCHEMBL29580111 0.91 SLC1A1 (0.69) GRIA2SLC1A1SLC7A5ALPIPKM
M-Fluorophenylalanine SCHEMBL288728 0.91 SLC1A1 (0.69) GRIA2SLC1A1SLC7A5ALPIPKM
SCHEMBL29217053 0.91 GRIA2 (0.84) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL944210 0.91 GRIA2 (0.84) GRIA2SLC7A5ALPIPKMPTGS1
SCHEMBL31688962 0.90 GRIA2 (0.69) GRIA2SLC7A5ALPIPKMPTGS1
M-Fluorophenylalanine SCHEMBL21057062 0.89 SLC1A1 (0.68) GRIA2SLC1A1SLC7A5ALPIPKM
M-Fluorophenylalanine SCHEMBL21057063 0.89 SLC1A1 (0.68) GRIA2SLC1A1SLC7A5ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 GRIA2 1319/4885SLC1A1 305/4885SLC7A5 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.