Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000728 | 0.81 | CYP1A2 (0.51) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL22775125 | 0.81 | CYP1A2 (0.51) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL16536084 | 0.81 | POLB (0.46) | CYP1A2KDM5CKDM5BKDM5AKDM5D | |
| SCHEMBL24248055 | 0.79 | HSD17B10 (0.51) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL18995811 | 0.79 | HSD17B10 (0.51) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL15495937 | 0.79 | HSD17B10 (0.51) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL17337885 | 0.79 | CYP1A2 (0.45) | CYP1A2KDM5CKDM5BKDM5AKDM5D | |
| SCHEMBL5566353 | 0.78 | HSD17B10 (0.50) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL29215396 | 0.78 | CYP1A2 (0.53) | CYP1A2HSD17B10SLC7A5PTGS1PKM | |
| SCHEMBL1568753 | 0.78 | NR3C2 (0.43) | CYP1A2HSD17B10KDM5CKDM5BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | CYP1A2 4562/4885HSD17B10 3828/4885SLC7A5 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.