Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22276388 | 0.74 | KDM4E (0.32) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22276460 | 0.73 | KDM4E (0.31) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22276400 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL22276441 | 0.70 | — | — | |
| SCHEMBL16861321 | 0.67 | — | — | |
| SCHEMBL3825796 | 0.65 | MEN1 (0.31) | KDM4E | |
| SCHEMBL10280520 | 0.61 | — | — | |
| SCHEMBL3152360 | 0.60 | — | — | |
| SCHEMBL648250 | 0.60 | IDO1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL22861810 | 0.60 | GABRA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099452-B1 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT LLC (US) | 2015-07-22 | — | — | EP | claimed |
| US-20100074842-A1 | Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | LIEBEL-FLARSHEIM COMPANY LLC | 2010-03-25 | — | — | US | claimed |
| EP-2099452-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | Mallinckrodt Inc. (US) | 2009-09-16 | — | — | EP | claimed |
| WO-2008061792-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT INC. (US) | 2008-05-29 | — | — | WO | claimed |
| EP-2099452-B1 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT LLC (US) | 2015-07-22 | — | — | EP | disclosed |
| US-9023315-B2 | Tricarbonyl complexes with tridentate chelators for myocardium imaging | MALLINCKRODT LLC (US) | 2015-05-05 | — | — | US | disclosed |
| US-8940273-B2 | Tricarbonyl complexes with tridentate chelators for myocardium imaging | MALLINCKRODT LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-20130129620-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | MALLINCKRODT LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131327-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | MALLINCKRODT LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-8372379-B2 | Technetium-99m (I) tricarbonyl complexes with tridentate chelators for myocardium imaging | MALLINCKRODT LLC (US) | 2013-02-12 | — | — | US | disclosed |
| US-20100074842-A1 | Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | LIEBEL-FLARSHEIM COMPANY LLC | 2010-03-25 | — | — | US | disclosed |
| EP-2099452-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | Mallinckrodt Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008061792-A2 | TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING | MALLINCKRODT INC. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131327-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | TNNT2, TNNI3, FABP3 | KDM4E 1256/4885ALDH1A1 3518/4885HPGD 3359/4885 |
| US-20100074842-A1 | Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | TNNT2, TNNI3, FABP3 | KDM4E 1564/4885ALDH1A1 3726/4885HPGD 3965/4885 |
| US-20130129620-A1 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging | TNNT2, TNNI3, FABP3 | KDM4E 1256/4885ALDH1A1 3518/4885HPGD 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.