SCHEMBL31371685

SCHEMBL31371685

CCOC(OCC)c1c([Si](C)(C)C)sc([Si](C)(C)C)c1F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31371793 0.79 THRB (0.30) THRB
SCHEMBL22688372 0.74 THRB (0.36) THRB
SCHEMBL5167373 0.63 THRB (0.31) THRB
SCHEMBL5421643 0.61
SCHEMBL14118944 0.59 LMNA (0.39) THRB
SCHEMBL19734526 0.58 BCHE (0.32)
SCHEMBL5421416 0.57
SCHEMBL2177010 0.57 MAPT (0.33)
SCHEMBL6921443 0.56
SCHEMBL28361855 0.55 THRB (0.40) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025034849-A1 FUSED PYRIDAZINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS THERAS, INC. (US) 2025-02-13 WO disclosed