SCHEMBL31372011

SCHEMBL31372011

N#Cc1c(F)cc(CCl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.41
KHK P50053 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31371999 0.87 TRPV4 (0.39) TRPV4
SCHEMBL10348466 0.86 MEN1 (0.35) TRPV4
SCHEMBL15129217 0.75 TRPV4 (0.46) TRPV4KHK
SCHEMBL15821506 0.75 TRPV4 (0.46) TRPV4KHK
SCHEMBL29738536 0.74 PNMT (0.32)
SCHEMBL17061815 0.74 PNMT (0.32)
SCHEMBL31371700 0.73 TRPV4 (0.41) TRPV4KHK
SCHEMBL18305809 0.72 TRPV4 (0.43) TRPV4KHK
SCHEMBL16177628 0.72 TRPV4 (0.43) TRPV4
SCHEMBL16545828 0.72 TRPV4 (0.43) TRPV4KHK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025036382-A1 SULFONAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海复宏汉霖生物医药有限公司 2025-02-20 WO disclosed