Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22075936 | 0.92 | PARP1 (0.43) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL22075928 | 0.92 | PARP1 (0.43) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL22075960 | 0.89 | MAPT (0.48) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL30369865 | 0.89 | MAPT (0.48) | ALDH1A1MEN1KMT2AMAPTTP53 | |
| SCHEMBL22111194 | 0.86 | PDK2 (0.42) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL22075945 | 0.85 | POLB (0.40) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL23499604 | 0.81 | PARP1 (0.52) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL30145026 | 0.81 | PARP1 (0.52) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL30457557 | 0.81 | HPGD (0.46) | PARP1PARP2ALDH1A1MEN1KMT2A | |
| SCHEMBL29040445 | 0.81 | HPGD (0.46) | PARP1PARP2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034789-A1 | ARYLBENZOISOXAZOLE COMPOUNDS AS IP6K AND IPMK DEGRADERS AND METHODS OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-02-13 | — | — | WO | disclosed |