Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151049 | 0.92 | EGLN1 (0.43) | EGLN1 | |
| SCHEMBL3146674 | 0.85 | CHRNB4 (0.43) | MAP4K4FFAR4EGLN1P2RX7 | |
| SCHEMBL3151015 | 0.85 | FFAR4 (0.40) | FFAR4EGLN1P2RX7 | |
| SCHEMBL3147012 | 0.84 | FFAR4 (0.44) | FFAR4P2RX7 | |
| SCHEMBL3150641 | 0.84 | P2RX7 (0.40) | FFAR4EGLN1P2RX7 | |
| SCHEMBL3150837 | 0.84 | MAP4K4 (0.43) | XDHLMNAMAP4K4L3MBTL1ALDH1A1 | |
| SCHEMBL3256998 | 0.84 | FFAR4 (0.42) | MAP4K4FFAR4EGLN1P2RX7 | |
| SCHEMBL3147063 | 0.83 | P2RX7 (0.44) | MAP4K4FFAR4EGLN1P2RX7 | |
| Hydrochloric Acid SCHEMBL3154957 | 0.83 | MAP4K4 (0.43) | XDHLMNAMAP4K4L3MBTL1ALDH1A1 | |
| SCHEMBL3147051 | 0.83 | FFAR4 (0.38) | FFAR4EGLN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |