Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650746 | 1.00 | ADRB2 (0.38) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL26650747 | 0.83 | ADRB2 (0.42) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL26650616 | 0.81 | ADRB2 (0.43) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL31373467 | 0.81 | ADRB2 (0.43) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL26650621 | 0.78 | ADRB2 (0.39) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL31373455 | 0.78 | ADRB2 (0.39) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL31373527 | 0.77 | GSK3A (0.40) | ADRB2FLT3FFAR2GSK3AGSK3B | |
| SCHEMBL26650564 | 0.77 | GSK3A (0.40) | ADRB2FLT3FFAR2GSK3AGSK3B | |
| SCHEMBL29141372 | 0.74 | GAA (0.39) | ADRB2FLT3NOS3NOS1NOS2 | |
| SCHEMBL31316098 | 0.73 | SLC6A4 (0.43) | ADRB2FFAR2ALDH1A1MAPTGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |