Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650621 | 1.00 | ADRB2 (0.39) | ADRB2FFAR2GSK3AGSK3BPLAU | |
| SCHEMBL31373467 | 0.86 | ADRB2 (0.43) | ADRB2FFAR2GSK3AGSK3BNOS3 | |
| SCHEMBL26650616 | 0.86 | ADRB2 (0.43) | ADRB2FFAR2GSK3AGSK3BNOS3 | |
| SCHEMBL30748650 | 0.81 | NCF1 (0.42) | FFAR2PLAUNOS3NOS1MCHR1 | |
| SCHEMBL31316098 | 0.81 | SLC6A4 (0.43) | ADRB2FFAR2GSK3AGSK3B | |
| SCHEMBL26646217 | 0.81 | SLC6A4 (0.43) | ADRB2FFAR2GSK3AGSK3B | |
| SCHEMBL31373527 | 0.79 | GSK3A (0.40) | ADRB2FFAR2GSK3AGSK3BFLT3 | |
| SCHEMBL26650564 | 0.79 | GSK3A (0.40) | ADRB2FFAR2GSK3AGSK3BFLT3 | |
| SCHEMBL31373458 | 0.78 | ADRB2 (0.38) | ADRB2FFAR2GSK3AGSK3BNOS3 | |
| SCHEMBL26650746 | 0.78 | ADRB2 (0.38) | ADRB2FFAR2GSK3AGSK3BNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |