Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650036 | 0.94 | HIF1A (0.45) | MAPTHIF1AMEN1KMT2AGAA | |
| SCHEMBL4134339 | 0.88 | MAPT (0.35) | MAPTHIF1AMEN1KMT2AGAA | |
| SCHEMBL5589442 | 0.74 | ALOX5 (0.42) | MAPTMEN1KMT2AALOX5PTGS2 | |
| Guaiacol SCHEMBL3959510 | 0.73 | TSHR (0.51) | MAPTALOX5PTGS2CYP1A2CYP3A4 | |
| SCHEMBL3137392 | 0.73 | ELANE (0.43) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL5587093 | 0.73 | ALOX5 (0.41) | MAPTMEN1KMT2AALOX5PTGS2 | |
| SCHEMBL5588873 | 0.73 | ALOX5 (0.41) | MAPTMEN1KMT2AALOX5PTGS2 | |
| SCHEMBL5589735 | 0.73 | ALOX5 (0.41) | MAPTMEN1KMT2AALOX5PTGS2 | |
| SCHEMBL5587997 | 0.73 | ALOX5 (0.41) | MAPTMEN1KMT2AALOX5PTGS2 | |
| SCHEMBL5588991 | 0.73 | ALOX5 (0.41) | MAPTMEN1KMT2AALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193784-A1 | Cosmetic compositions containing an ester derivative of 2-pyrrolidinone 4-carboxy and a lipophilic triazine filter, with use of said derivative as a solvent of a lipophilic triazine filter | L'OREAL (FR) | 2010-06-09 | — | — | EP | disclosed |