Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650037 | 0.95 | ELANE (0.45) | ELANECNR1CNR2CTSGMEN1 | |
| SCHEMBL627672 | 0.87 | CYP1A2 (0.39) | ELANECNR1CNR2MEN1KMT2A | |
| SCHEMBL2709504 | 0.87 | CYP1A2 (0.41) | MAPTALDH1A1KDM4EATMNPSR1 | |
| SCHEMBL17436829 | 0.83 | RARB (0.39) | MEN1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL404718 | 0.81 | PPARA (0.41) | MAPTKDM4EUSP2ATMNPSR1 | |
| SCHEMBL1722952 | 0.78 | PAX8 (0.35) | ELANECNR1CNR2MEN1MAPT | |
| SCHEMBL17294439 | 0.74 | THRA (0.35) | TLR8 | |
| SCHEMBL3137386 | 0.73 | MAPT (0.40) | ELANECNR1CNR2MEN1MAPT | |
| SCHEMBL29532574 | 0.72 | SMPD1 (0.43) | ALDH1A1ALOX5 | |
| SCHEMBL30497724 | 0.71 | CYP1A2 (0.57) | KDM4ECYP1A2CYP2C19TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193784-A1 | Cosmetic compositions containing an ester derivative of 2-pyrrolidinone 4-carboxy and a lipophilic triazine filter, with use of said derivative as a solvent of a lipophilic triazine filter | L'OREAL (FR) | 2010-06-09 | — | — | EP | disclosed |