Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 6/20 | 0.61 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.60 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374351 | 0.91 | LDHA (0.75) | LDHAPTGER1CHEK1RAB9AALDH1A1 | |
| SCHEMBL31374354 | 0.90 | CHEK1 (0.62) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL31374346 | 0.86 | CHEK1 (0.56) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL31374419 | 0.84 | CHEK1 (0.70) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL31374433 | 0.83 | CHEK1 (0.57) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL17900391 | 0.79 | PTGER1 (0.74) | LDHAPTGER1CHEK1RAB9AALDH1A1 | |
| SCHEMBL31374435 | 0.76 | LDHA (0.59) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL31374400 | 0.74 | LDHA (0.57) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL31374375 | 0.74 | LDHA (0.79) | LDHAPTGER1CHEK1RAB9ASMN1; SMN2 | |
| SCHEMBL31374372 | 0.74 | NPC1 (0.47) | CHEK1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192171-A | Small molecule compounds and their use in vitro expansion of hematopoietic stem cells and/or progenitor cells | 上海交通大学医学院 | 2024-12-27 | — | — | CN | disclosed |