Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345119 | 0.75 | NPY5R (0.73) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL1144023 | 0.74 | RAB9A (0.71) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL31374351 | 0.74 | LDHA (0.75) | NPC1RAB9ANPY5RALDH1A1KDM4E | |
| SCHEMBL31374341 | 0.74 | LDHA (0.61) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL31374354 | 0.73 | CHEK1 (0.62) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL15729859 | 0.73 | NPC1 (0.57) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL31374374 | 0.72 | L3MBTL1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30229566 | 0.71 | NPY5R (0.64) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL31374419 | 0.70 | CHEK1 (0.70) | NPC1RAB9ANPY5RSMN1; SMN2ALDH1A1 | |
| SCHEMBL31374346 | 0.70 | CHEK1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192171-A | Small molecule compounds and their use in vitro expansion of hematopoietic stem cells and/or progenitor cells | 上海交通大学医学院 | 2024-12-27 | — | — | CN | disclosed |