Gamma-Aminobutyric Acid

Gamma-Aminobutyric Acid

SCHEMBL3137456

NCCC(=O)O.NCCCC(=O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.88
TSHR P16473 3/20 0.88
THRB P10828 2/20 0.88
BLM P54132 2/20 0.88
KMT2A Q03164 2/20 0.88
NPSR1 Q6W5P4 2/20 0.88
GABRR1 P24046 2/20 0.88
GABRR3 A8MPY1 1/20 0.88
GABRP O00591 1/20 0.88
GABRD O14764 1/20 0.88
HDAC3 O15379 1/20 0.88
GABBR2 O75899 1/20 0.88
CYP1A2 P05177 1/20 0.88
GABRA1 P14867 1/20 0.88
GABRB1 P18505 1/20 0.88
GABRG2 P18507 1/20 0.88
GABRB3 P28472 1/20 0.88
GABRR2 P28476 1/20 0.88
SLC6A1 P30531 1/20 0.88
GABRA5 P31644 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamma-Aminobutyric Acid SCHEMBL27860343 0.94 LMNA (0.88) LMNATSHRTHRBBLMKMT2A
Gamma-Aminobutyric Acid SCHEMBL190459 0.94 LMNA (1.00) LMNATSHRTHRBBLMKMT2A
Gamma-Aminobutyric Acid SCHEMBL1330421 0.94
Gamma-Aminobutyric Acid SCHEMBL4878 0.94
Gamma-Aminobutyric Acid SCHEMBL3973563 0.94 LMNA (1.00) LMNATSHRTHRBBLMKMT2A
Gamma-Aminobutyric Acid SCHEMBL3017607 0.92 LMNA (0.83) LMNATSHRTHRBBLMKMT2A
Gamma-Aminobutyric Acid SCHEMBL25327475 0.91
Gamma-Aminobutyric Acid SCHEMBL587530 0.91
Gamma-Aminobutyric Acid SCHEMBL20593981 0.91 LMNA (0.94) LMNATSHRTHRBBLMKMT2A
Gamma-Aminobutyric Acid SCHEMBL20593982 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4342890-A1 PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS Erasmus University Rotterdam Medical Center (NL) 2024-03-27 EP claimed
CN-112546296-B Composite bone repair material with light display effect and self-positioning function and preparation method thereof 中鼎凯瑞科技成都有限公司 2022-04-22 CN claimed
CN-112546296-A Composite bone repair material with light display effect and self-positioning function and preparation method thereof 中鼎凯瑞科技成都有限公司 2021-03-26 CN claimed
EP-1592801-B1 Method for identifying activated polymer complexes for secondary site-specific modification of protein target groups. ADVANCED PROTEOME THERAPEUTICS (US) 2010-05-05 EP claimed
US-7169759-B1 Tetrapeptide inhibitors of β-secretase ELAN PHARMACEUTICALS, INC. (US) 2007-01-30 US claimed
EP-1192177-A1 STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE Elan Pharmaceuticals, Inc. (US) 2002-04-03 EP claimed
WO-2000077030-A1 STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE ELAN PHARMACEUTICALS, INC. (US) 2000-12-21 WO claimed
US-4755379-A Polymers substituted by groups conferring anti-coagulant properties on them, process for their preparation, articles and compositions made therefrom and uses thereof Jozefonvicz, Jacqueline (FR) 1988-07-05 US claimed
CN-112546296-B Composite bone repair material with light display effect and self-positioning function and preparation method thereof 中鼎凯瑞科技成都有限公司 2022-04-22 CN disclosed
CN-112546296-A Composite bone repair material with light display effect and self-positioning function and preparation method thereof 中鼎凯瑞科技成都有限公司 2021-03-26 CN disclosed
US-20060051587-A1 Thermosetting resin composition and adhesive film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-09 US disclosed
EP-0555336-B1 HOMOBIFUNCTIONAL AGENTS FOR COUPLING ENZYMES AND THE LIKE TO ANTIBODIES AND THE LIKE ABBOTT LAB (US) 1996-07-24 EP disclosed
EP-0225465-A1 Improved fusible powdered metal paste SCM CORPORATION (US) 1987-06-16 EP disclosed
US-4619715-A NONHYDROCARBON RESINOUS BINDER DISPERSED IN NONAQUEOUS ORGANIC LIQUID SCM CORPORATION (US) 1986-10-28 US disclosed
EP-0140344-A2 Paste vehicle for fusible powdered metal paste SCM CORPORATION (US) 1985-05-08 EP disclosed