SCHEMBL3137484

SCHEMBL3137484

F[B-](F)(F)F.c1ccc([S+](c2ccccc2)c2cccc3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
ALDH1A1 P00352 6/20 0.36
CYP2A6 P11509 3/20 0.36
TSHR P16473 3/20 0.36
HSD17B10 Q99714 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 4/20 0.34
HPGD P15428 3/20 0.34
CYP3A4 P08684 2/20 0.34
KEAP1 Q14145 1/20 0.34
CDC25B P30305 2/20 0.34
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29973074 0.92 ALDH1A1 (0.42) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
SCHEMBL98432 0.92 ALDH1A1 (0.42) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
Bromide SCHEMBL3137561 0.90 ALDH1A1 (0.40) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
SCHEMBL31229937 0.89 ALDH1A1 (0.36) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
SCHEMBL30951258 0.88 ALDH1A1 (0.42) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
SCHEMBL98512 0.88 ALDH1A1 (0.42) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
SCHEMBL3140894 0.85 ALDH1A1 (0.33) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
Perchlorate SCHEMBL3140950 0.85 ALDH1A1 (0.36) NR4A1NR4A2NR4A3ALDH1A1CYP2A6
SCHEMBL3130394 0.83
SCHEMBL3129005 0.81 ALDH1A1 (0.33) NR4A1NR4A2NR4A3ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 NR4A1 2541/4885NR4A2 3004/4885NR4A3 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.