Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.37 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612233 | 0.86 | ENPP2 (0.37) | CYP1A2CYP3A4CYP2C9CYP2C19F2RL3 | |
| SCHEMBL21922351 | 0.86 | ENPP2 (0.37) | CYP1A2CYP3A4CYP2C9CYP2C19F2RL3 | |
| SCHEMBL9156095 | 0.84 | KDR (0.40) | MKNK1MKNK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31375488 | 0.84 | KDR (0.40) | MKNK1MKNK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9154058 | 0.81 | ELOVL1 (0.41) | MKNK1MKNK2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9158700 | 0.79 | RARB (0.41) | CYP1A2CYP3A4KDRTEKELOVL1 | |
| SCHEMBL3059303 | 0.78 | MKNK1 (0.57) | MKNK1MKNK2KDRTEKFYN | |
| SCHEMBL9155978 | 0.78 | MAPT (0.46) | S1PR1 | |
| SCHEMBL1819377 | 0.77 | MAPT (0.47) | MKNK1MKNK2KDRELOVL1FYN | |
| SCHEMBL8027367 | 0.75 | PPARA (0.49) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |