Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 4/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628311 | 0.87 | MEN1 (0.35) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL31375494 | 0.87 | MEN1 (0.35) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL31375584 | 0.85 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL31628211 | 0.85 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL31375598 | 0.85 | KMT2A (0.37) | KMT2AHDAC1HDAC8HDAC6CASP1 | |
| SCHEMBL31628071 | 0.85 | KMT2A (0.37) | KMT2AHDAC1HDAC8HDAC6CASP1 | |
| SCHEMBL29796820 | 0.84 | HDAC1 (0.39) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL26962726 | 0.84 | HDAC1 (0.39) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL30830316 | 0.82 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL29796987 | 0.81 | HPGD (0.41) | KMT2AHDAC1HDAC8HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |