Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628071 | 1.00 | KMT2A (0.37) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL31375523 | 0.85 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL26962726 | 0.84 | HDAC1 (0.39) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL29796820 | 0.84 | HDAC1 (0.39) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL26962078 | 0.81 | HPGD (0.41) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL29796987 | 0.81 | HPGD (0.41) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL31628211 | 0.81 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL31375584 | 0.81 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL30830316 | 0.81 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL20264133 | 0.80 | SMN1; SMN2 (0.48) | KMT2AHDAC1HDAC8HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |