Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628211 | 1.00 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL29796820 | 0.90 | HDAC1 (0.39) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL26962726 | 0.90 | HDAC1 (0.39) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL30830316 | 0.86 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL31628061 | 0.85 | GAA (0.34) | GAA | |
| SCHEMBL31375537 | 0.85 | GAA (0.34) | GAA | |
| SCHEMBL31375523 | 0.85 | KMT2A (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL31628166 | 0.85 | HPGD (0.36) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL29796987 | 0.84 | HPGD (0.41) | KMT2AHDAC1HDAC8HDAC6HPGD | |
| SCHEMBL26962078 | 0.84 | HPGD (0.41) | KMT2AHDAC1HDAC8HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |