Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 2/20 | 0.34 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628115 | 1.00 | TRPC3 (0.34) | TRPC3TRPC7GPR119ENPP2ATXN2 | |
| SCHEMBL31628207 | 0.86 | GPR119 (0.35) | TRPC3TRPC7GPR119ENPP2ATXN2 | |
| SCHEMBL31375547 | 0.86 | GPR119 (0.35) | TRPC3TRPC7GPR119ENPP2ATXN2 | |
| SCHEMBL31628259 | 0.85 | GAA (0.33) | GAA | |
| SCHEMBL31375516 | 0.85 | GAA (0.33) | GAA | |
| SCHEMBL31375494 | 0.80 | MEN1 (0.35) | ENPP2ATXN2ALDH1A1SMN1; SMN2PDE4B | |
| SCHEMBL31628311 | 0.80 | MEN1 (0.35) | ENPP2ATXN2ALDH1A1SMN1; SMN2PDE4B | |
| SCHEMBL26962039 | 0.77 | XIAP (0.36) | TRPC3TRPC7GPR119ALDH1A1PDE4B | |
| SCHEMBL26962120 | 0.77 | JAK2 (0.34) | GPR119ENPP2SMN1; SMN2TBK1 | |
| SCHEMBL29797169 | 0.77 | GAA (0.37) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |