Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.34 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628207 | 1.00 | GPR119 (0.35) | GPR119USP30PDE4BTRPC3TRPC7 | |
| SCHEMBL31375581 | 0.86 | TRPC3 (0.34) | GPR119PDE4BTRPC3TRPC7PARP1 | |
| SCHEMBL31628115 | 0.86 | TRPC3 (0.34) | GPR119PDE4BTRPC3TRPC7PARP1 | |
| SCHEMBL31375588 | 0.80 | USP30 (0.35) | USP30PDE4BCTSDBACE1PARP1 | |
| SCHEMBL31628135 | 0.80 | USP30 (0.35) | USP30PDE4BCTSDBACE1PARP1 | |
| SCHEMBL31375572 | 0.77 | GAA (0.34) | GAABRD4 | |
| SCHEMBL31628193 | 0.77 | GAA (0.34) | GAABRD4 | |
| SCHEMBL31375516 | 0.76 | GAA (0.33) | GAABRD4 | |
| SCHEMBL31628259 | 0.76 | GAA (0.33) | GAABRD4 | |
| SCHEMBL30675704 | 0.76 | USP30 (0.36) | USP30CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |