Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26962726 | 0.89 | HDAC1 (0.39) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL29796820 | 0.89 | HDAC1 (0.39) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL31628211 | 0.85 | KMT2A (0.36) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL30830316 | 0.85 | KMT2A (0.36) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL31375584 | 0.85 | KMT2A (0.36) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL29796987 | 0.82 | HPGD (0.41) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL26962078 | 0.82 | HPGD (0.41) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL31375565 | 0.82 | LMNA (0.54) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL20279961 | 0.82 | LMNA (0.54) | HPGDLMNAALDH1A1KMT2AHDAC1 | |
| SCHEMBL20264133 | 0.81 | SMN1; SMN2 (0.48) | HPGDLMNAALDH1A1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568959-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |