Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926335 | 0.89 | PTGER1 (0.67) | PTGER1MRGPRX4MCL1NPC1RAB9A | |
| SCHEMBL5460706 | 0.88 | PTGER1 (0.65) | PTGER1MRGPRX4KMT2ALRRK2CYP2C9 | |
| SCHEMBL21447041 | 0.87 | NPC1 (0.58) | PTGER1MRGPRX4NPC1RAB9AKMT2A | |
| SCHEMBL11357851 | 0.87 | MAOB (0.61) | PTGER1MRGPRX4MCL1LRRK2CYP2C9 | |
| SCHEMBL1425720 | 0.87 | PTGER1 (0.56) | PTGER1MRGPRX4MCL1NPC1RAB9A | |
| SCHEMBL4939266 | 0.86 | MAOB (0.60) | MCL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1315450 | 0.85 | PTGER1 (0.59) | PTGER1MRGPRX4MCL1NPC1RAB9A | |
| SCHEMBL21434703 | 0.84 | PTGER1 (0.57) | PTGER1MRGPRX4MCL1NPC1RAB9A | |
| SCHEMBL11355488 | 0.84 | PTGER1 (0.54) | PTGER1MRGPRX4MCL1NPC1RAB9A | |
| SCHEMBL19361431 | 0.84 | PTGES (0.52) | PTGER1MCL1LRRK2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |