Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 14/20 | 0.52 |
| ▸ | MT-CO1 | P00395 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657553 | 0.88 | CCKAR (0.67) | CCKARMT-CO1CNR2 | |
| SCHEMBL3137597 | 0.82 | CCKAR (0.66) | CCKARMT-CO1CNR2 | |
| SCHEMBL2152585 | 0.81 | CCKAR (0.79) | CCKAR | |
| SCHEMBL3980545 | 0.80 | CCKAR (0.65) | CCKAR | |
| SCHEMBL12477368 | 0.78 | CCKAR (0.68) | CCKAR | |
| SCHEMBL2357628 | 0.76 | CCKAR (0.68) | CCKARMT-CO1CNR2MGLL | |
| SCHEMBL2152460 | 0.74 | CCKAR (0.69) | CCKAR | |
| SCHEMBL3612093 | 0.73 | CCKAR (0.63) | CCKAR | |
| SCHEMBL12510547 | 0.71 | CCKAR (0.66) | CCKAR | |
| SCHEMBL2923432 | 0.70 | CCKAR (0.75) | CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010519-A2 | SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007120655-A2 | SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | claimed |