Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 10/20 | 0.35 |
| ▸ | HTR2C | P28335 | 9/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376030 | 0.74 | MEN1 (0.40) | KMT2AMEN1MAPK1TDP1L3MBTL1 | |
| SCHEMBL13836388 | 0.73 | KMT2A (0.48) | KMT2AMEN1MAPK1TDP1L3MBTL1 | |
| SCHEMBL31375950 | 0.72 | TGFBR1 (0.44) | HTR2AHTR2C | |
| SCHEMBL18983526 | 0.70 | AKT1 (0.35) | HTR2AHTR2C | |
| SCHEMBL23087496 | 0.70 | HSD11B1 (0.49) | KMT2AHIF1AHTR2AHTR2C | |
| SCHEMBL2273938 | 0.70 | HTR2A (0.47) | HIF1AHTR2AHTR2C | |
| SCHEMBL23087258 | 0.70 | PRMT5 (0.47) | HIF1AHTR2AHTR2C | |
| SCHEMBL1420436 | 0.69 | KMT2A (0.46) | KMT2AMEN1MAPK1TDP1L3MBTL1 | |
| SCHEMBL12681399 | 0.67 | GAA (0.41) | TDP1HIF1AHTR2AHTR2C | |
| SCHEMBL23105041 | 0.67 | PRMT5 (0.44) | MAPK1HIF1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |