SCHEMBL31376150

SCHEMBL31376150

CC(C)c1cc(F)cc(Br)c1Cl

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
KCNH2 Q12809 1/20 0.31
LMNA P02545 1/20 0.31
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26203728 0.84 GABRA1 (0.41) GABRA1GABRB1KCNH2LMNAPSEN1
SCHEMBL21316937 0.83 GABRA1 (0.37) GABRA1GABRB1KCNH2LMNAPSEN1
SCHEMBL25839081 0.78 GABRA1 (0.37) GABRA1GABRB1
SCHEMBL17125232 0.77 LMNA (0.39) GABRA1GABRB1KCNH2LMNAPSEN1
SCHEMBL25839065 0.77 GABRA1 (0.35) GABRA1GABRB1
SCHEMBL29325148 0.77 GABRA1 (0.35) GABRA1GABRB1
SCHEMBL1494504 0.77 GAA (0.35)
SCHEMBL23063467 0.75 GABRA1 (0.54) GABRA1GABRB1LMNA
SCHEMBL20609888 0.75 GAA (0.36) GABRA1GABRB1
SCHEMBL19475121 0.75 GABRA1 (0.41) GABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778340-B Organic compound, application thereof and organic electroluminescent device using same 合肥鼎材科技有限公司 2025-05-02 CN disclosed
CN-112898322-B Organic compound, application thereof and organic electroluminescent device containing same 北京鼎材科技有限公司 2025-02-18 CN disclosed