Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2184231 | 0.82 | ANO1 (0.47) | ANO1MEN1KMT2AANO2RAB9A | |
| SCHEMBL2179982 | 0.81 | CASP3 (0.55) | ANO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL2178832 | 0.78 | KCNQ3 (0.58) | ANO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL2182642 | 0.78 | ANO1 (0.53) | ANO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL12414182 | 0.76 | CASP3 (0.48) | ANO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL15241643 | 0.75 | TP53 (0.46) | ANO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL1953704 | 0.74 | ANO1 (0.59) | ANO1ANO2TP53SMN1; SMN2 | |
| SCHEMBL12434639 | 0.73 | CASP3 (0.68) | ANO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL12434677 | 0.73 | RAB9A (0.43) | ANO1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL12414185 | 0.71 | CASP3 (0.71) | ANO1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025295-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-04 | — | — | WO | disclosed |