Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.56 |
| ▸ | CCR1 | P32246 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3052654 | 0.88 | CCR2 (0.66) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3054500 | 0.86 | CCR2 (0.53) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3050361 | 0.86 | CCR2 (0.55) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3153386 | 0.85 | CCR2 (0.52) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3153394 | 0.85 | CCR2 (0.52) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3153909 | 0.85 | KMT2A (0.57) | CCR2CCR1CYP3A4CYP2C9PTGDR | |
| Hydrochloric Acid SCHEMBL3153990 | 0.84 | CCR2 (0.51) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3153175 | 0.84 | CCR2 (0.53) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3153999 | 0.84 | CCR2 (0.51) | CCR2CCR1KCNH2CYP1A2CYP3A4 | |
| SCHEMBL3053653 | 0.84 | PTGDR2 (0.49) | CCR2CCR1KCNH2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074083-B1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-06-19 | — | — | EP | disclosed |
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB1, BDKRB2, TRPV1 | CCR2 417/4885CCR1 358/4885KCNH2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.