Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141614 | 0.79 | CYP3A4 (0.61) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL3138220 | 0.78 | HSD17B10 (0.55) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL29549758 | 0.78 | CYP3A4 (1.00) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL105866 | 0.78 | CYP3A4 (1.00) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL29365557 | 0.78 | CYP3A4 (1.00) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL23924225 | 0.78 | CYP3A4 (1.00) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL3466627 | 0.78 | ALDH1A1 (0.43) | CYP3A4HSD17B10ALDH1A1TDP1TSHR | |
| SCHEMBL3136343 | 0.76 | ALOX15 (0.57) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL6653834 | 0.76 | CYP3A4 (0.94) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL20945278 | 0.76 | ALOX15 (0.94) | CYP3A4HSD17B10ALOX15BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | claimed |
| CN-1997637-A | Novel o-aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2007-07-11 | — | — | CN | claimed |
| EP-1768971-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006007896-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | claimed |
| US-7641702-B2 | O-Aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2010-01-05 | — | — | US | disclosed |
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | disclosed |
| CN-1997637-A | Novel o-aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| EP-1768971-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006007896-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | CBR3, KRT18, F12 | CYP3A4 526/4885HSD17B10 2013/4885ALOX15 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.