Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.69 |
| ▸ | PTPN12 | Q05209 | 6/20 | 0.69 |
| ▸ | PTPN22 | Q9Y2R2 | 6/20 | 0.69 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.64 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | MITF | O75030 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GLP1R | P43220 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376976 | 0.97 | NPC1 (0.71) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL18539156 | 0.95 | NPC1 (0.80) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31377003 | 0.93 | GPR35 (0.64) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31376994 | 0.91 | NPC1 (0.65) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31376962 | 0.91 | GPR35 (0.66) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31376947 | 0.91 | GPR35 (0.63) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31376972 | 0.91 | GPR35 (0.63) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31377011 | 0.90 | GPR35 (0.65) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31377019 | 0.89 | POLB (0.62) | NPC1GPR35PTPN12PTPN22PTPN7 | |
| SCHEMBL31376925 | 0.89 | GPR35 (0.63) | NPC1GPR35PTPN12PTPN22PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064325-A1 | GPR35 MODULATORS | PROMETHEUS BIOSCIENCES, INC. (US) | 2025-03-27 | — | — | WO | disclosed |