SCHEMBL31377271

SCHEMBL31377271

CCOC(=O)Cc1cnc[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
CYP3A4 P08684 1/20 0.58
GABRA1 P14867 1/20 0.58
TSHR P16473 1/20 0.58
NFKB1 P19838 1/20 0.58
GABRR1 P24046 1/20 0.58
GABRR2 P28476 1/20 0.58
GABRA5 P31644 1/20 0.58
GABRB2 P47870 1/20 0.58
GABRA4 P48169 1/20 0.58
KDM4E B2RXH2 2/20 0.56
PMP22 Q01453 2/20 0.56
MAPT P10636 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.47
PKM P14618 1/20 0.46
QPCT Q16769 1/20 0.45
QPCTL Q9NXS2 1/20 0.45
HRH3 Q9Y5N1 4/20 0.44
POLB P06746 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27303234 0.83 HRH3 (0.50) QPCTQPCTLHRH3HRH4
SCHEMBL4251397 0.82 ALDH1A1 (0.61) ALDH1A1CYP3A4GABRA1TSHRNFKB1
SCHEMBL27475925 0.79 ALDH1A1 (0.58) ALDH1A1CYP3A4GABRA1TSHRNFKB1
SCHEMBL12478684 0.79 KMT2A (0.51) ALDH1A1TSHRKDM4ESMN1; SMN2PKM
SCHEMBL1387582 0.78 ALDH1A1 (0.56) ALDH1A1CYP3A4GABRA1TSHRNFKB1
SCHEMBL18814492 0.77 ALDH1A1 (0.44) ALDH1A1CYP3A4GABRA1TSHRNFKB1
SCHEMBL8918572 0.77 ALDH1A1 (0.63) ALDH1A1CYP3A4GABRA1TSHRNFKB1
SCHEMBL890227 0.76
Methyl Alcohol SCHEMBL11465646 0.76 ALDH1A1 (0.68) ALDH1A1CYP3A4GABRA1TSHRNFKB1
SCHEMBL16676578 0.76 HRH3 (0.51) ALDH1A1CYP3A4GABRA1TSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ALDH1A1 2774/4885CYP3A4 4137/4885GABRA1 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.