SCHEMBL31377380

SCHEMBL31377380

CC(=O)O[C@@H]1[C@@H](O)CN[C@@H]1Cc1ccc(-c2cn(-c3ccnc(N)n3)nn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.50
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ LMNA P02545 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ HIF1A Q16665 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ SLC2A1 P11166 1/20 0.50
▸ GBA1 P04062 5/20 0.37
▸ GLA P06280 1/20 0.37
▸ EP300 Q09472 5/20 0.36
▸ S1PR1 P21453 1/20 0.34
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31377407 0.79 ABHD6 (0.35) EP300S1PR1
SCHEMBL31421234 0.75 CYP2D6 (0.55) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377376 0.74 CYP2D6 (0.64) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL30860164 0.70 CYP2D6 (0.77) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377219 0.70 CYP2D6 (0.62) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377367 0.69 CYP2D6 (0.75) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31377127 0.69 CYP2D6 (0.75) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL31454028 0.69 CYP2D6 (0.75) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
SCHEMBL29351359 0.69 CYP2D6 (0.74) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A
Anisomycin SCHEMBL8331774 0.68 SMN1; SMN2 (1.00) CYP2D6SMN1; SMN2LMNAMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS CYP2D6 2734/4885SMN1; SMN2 1694/4885LMNA 2869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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