SCHEMBL31377407

SCHEMBL31377407

CC(=O)O[C@H]1[C@@H](Cc2ccc(-c3cn(-c4ccnc(N)n4)nn3)cc2)N(C(=O)OC(C)(C)C)C[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ABHD6 Q9BV23 2/20 0.35
▸ DAGLA Q9Y4D2 1/20 0.35
▸ S1PR1 P21453 9/20 0.34
▸ GRM5 P41594 1/20 0.34
▸ GRM1 Q13255 1/20 0.34
▸ EP300 Q09472 4/20 0.32
▸ ABL1 P00519 2/20 0.32
▸ BCR P11274 2/20 0.32
▸ P2RY14 Q15391 1/20 0.32
▸ HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31377434 0.83 ABHD6 (0.40) ABHD6DAGLAS1PR1ABL1BCR
SCHEMBL31377380 0.79 CYP2D6 (0.50) S1PR1EP300
SCHEMBL31377215 0.77 CYP2D6 (0.34) ABHD6DAGLAABL1BCR
SCHEMBL31377351 0.76 NR1H2 (0.40) —
SCHEMBL31377105 0.75 CYP2D6 (0.38) —
SCHEMBL31377217 0.74 RORC (0.38) —
SCHEMBL31377193 0.74 VEGFA (0.38) —
SCHEMBL31377211 0.74 NR1H2 (0.45) HDAC1
SCHEMBL31377178 0.74 NR1H2 (0.45) HDAC1
SCHEMBL31377297 0.73 SMN1; SMN2 (0.51) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ABHD6 2017/4885DAGLA 3713/4885S1PR1 2157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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