Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377439 | 0.88 | ATM (0.43) | SIRT2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL31377480 | 0.85 | SIRT2 (0.48) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377506 | 0.82 | ALDH1A1 (0.42) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377470 | 0.82 | CHEK2 (0.49) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377431 | 0.81 | KDM4E (0.42) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377438 | 0.81 | ADORA2A (0.43) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377524 | 0.81 | JMJD6 (0.46) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377471 | 0.81 | NPC1 (0.54) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377518 | 0.81 | MEN1 (0.42) | SIRT2SIRT1KDM4EALDH1A1HPGD | |
| SCHEMBL31377488 | 0.74 | MAPT (0.43) | SIRT2SIRT1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |