Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377505 | 1.00 | MAPT (0.43) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL31377439 | 0.86 | ATM (0.43) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL31377504 | 0.84 | SIRT2 (0.42) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL31377447 | 0.77 | MAPT (0.46) | MAPTELANELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3790281 | 0.74 | ALDH1A1 (0.51) | MAPTLMNAALDH1A1SMN1; SMN2SIRT2 | |
| SCHEMBL31377415 | 0.74 | SIRT2 (0.45) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL31377412 | 0.74 | TP53 (0.48) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL18548712 | 0.72 | ALDH1A1 (0.49) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL29660237 | 0.72 | ALDH1A1 (0.49) | MAPTATMELANELMNAALDH1A1 | |
| SCHEMBL14492426 | 0.72 | ALDH1A1 (0.54) | MAPTATMLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |