Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377424 | 0.90 | KLKB1 (0.46) | MAPTTHRBNPC1NLRP3TP53 | |
| SCHEMBL31377529 | 0.87 | NPSR1 (0.44) | MAPTNPC1NLRP3TP53SMN1; SMN2 | |
| SCHEMBL31377473 | 0.84 | MAPT (0.47) | MAPTNPC1NLRP3TP53SMN1; SMN2 | |
| SCHEMBL31377542 | 0.84 | MAPT (0.43) | MAPTTHRBNPC1NLRP3TP53 | |
| SCHEMBL31377447 | 0.83 | MAPT (0.46) | MAPTNPC1NLRP3TP53SMN1; SMN2 | |
| SCHEMBL31377553 | 0.81 | MAPT (0.42) | MAPTNPC1NLRP3TP53SMN1; SMN2 | |
| SCHEMBL31377518 | 0.80 | MEN1 (0.42) | MAPTNPC1TP53GAAALDH1A1 | |
| SCHEMBL31377491 | 0.78 | CD274 (0.38) | MAPTTHRBNPC1NLRP3TP53 | |
| SCHEMBL31377534 | 0.77 | MAPT (0.38) | MAPTNPC1NLRP3ALDH1A1KDM4E | |
| SCHEMBL31377471 | 0.69 | NPC1 (0.54) | MAPTNPC1TP53SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |