Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377473 | 0.86 | MAPT (0.47) | MAPTNPC1NLRP3SMN1; SMN2KDM4E | |
| SCHEMBL31377447 | 0.84 | MAPT (0.46) | MAPTNPC1NLRP3SMN1; SMN2KDM4E | |
| SCHEMBL31377529 | 0.84 | NPSR1 (0.44) | MAPTNPC1NLRP3SMN1; SMN2KDM4E | |
| SCHEMBL31377424 | 0.82 | KLKB1 (0.46) | MAPTNPC1NLRP3SMN1; SMN2KDM4E | |
| SCHEMBL31377542 | 0.82 | MAPT (0.43) | MAPTNPC1NLRP3SMN1; SMN2KDM4E | |
| SCHEMBL31377484 | 0.81 | MAPT (0.41) | MAPTNPC1NLRP3SMN1; SMN2KDM4E | |
| SCHEMBL31377506 | 0.79 | ALDH1A1 (0.42) | NPC1NLRP3RXFP1SMN1; SMN2KDM4E | |
| SCHEMBL31377534 | 0.76 | MAPT (0.38) | MAPTNPC1NLRP3KDM4EALDH1A1 | |
| SCHEMBL23037685 | 0.69 | NLRP3 (0.45) | NLRP3GHSRADORA3 | |
| SCHEMBL31613882 | 0.69 | MAPT (0.44) | MAPTNPC1RXFP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |