Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | SLC26A6 | Q9BXS9 | 4/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31377473 | 0.91 | MAPT (0.47) | MAPTGAANPC1NLRP3SMN1; SMN2 | |
| SCHEMBL31377529 | 0.87 | NPSR1 (0.44) | MAPTGAANPC1NLRP3SMN1; SMN2 | |
| SCHEMBL31377553 | 0.84 | MAPT (0.42) | MAPTGAANPC1NLRP3SMN1; SMN2 | |
| SCHEMBL31377424 | 0.83 | KLKB1 (0.46) | MAPTGAANPC1NLRP3SMN1; SMN2 | |
| SCHEMBL31377542 | 0.83 | MAPT (0.43) | MAPTGAANPC1NLRP3SMN1; SMN2 | |
| SCHEMBL31377484 | 0.83 | MAPT (0.41) | MAPTGAANPC1NLRP3SMN1; SMN2 | |
| SCHEMBL31377488 | 0.77 | MAPT (0.43) | MAPTNPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31377439 | 0.77 | ATM (0.43) | MAPTGAANPC1SMN1; SMN2KDM4E | |
| SCHEMBL31377505 | 0.77 | MAPT (0.43) | MAPTNPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31377504 | 0.75 | SIRT2 (0.42) | MAPTNPC1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219640-A | Nitrogen-containing ternary condensed ring derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |