SCHEMBL31377495

SCHEMBL31377495

C#CCO[C@@H]1[C@@H](OC(=O)OC(C)(C)C)CN(C(=O)OC(C)(C)C)[C@@H]1Cc1ccc(OC)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.37
▸ LMNA P02545 3/20 0.37
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ SMN1; SMN2 Q16637 4/20 0.34
▸ STS P08842 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ TP53 P04637 2/20 0.33
▸ MAOB P27338 1/20 0.33
▸ CCR3 P51677 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CYP2D6 P10635 3/20 0.32
▸ CDK2 P24941 1/20 0.32
▸ CCNA1 P78396 1/20 0.32
▸ CDK5 Q00535 1/20 0.32
▸ CDK5R1 Q15078 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32687577 0.88 ALDH1A1 (0.37) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31420805 0.87 ALDH1A1 (0.41) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL32687357 0.86 ALDH1A1 (0.38) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31377328 0.86 SMN1; SMN2 (0.43) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31377355 0.84 ALDH1A1 (0.37) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31377243 0.84 ALDH1A1 (0.39) ALDH1A1LMNAMEN1KMT2ASTS
SCHEMBL31377106 0.83 ALDH1A1 (0.39) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31377340 0.83 ALDH1A1 (0.39) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31421133 0.83 ALDH1A1 (0.40) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31377196 0.83 ALDH1A1 (0.40) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ALDH1A1 2774/4885LMNA 2869/4885MEN1 867/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ALDH1A1 2630/4885LMNA 3037/4885MEN1 798/4885
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 ALDH1A1 3887/4885LMNA 2918/4885MEN1 1248/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS ALDH1A1 3241/4885LMNA 2258/4885MEN1 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback