SCHEMBL3137759

SCHEMBL3137759

NC(=O)CCCCNS(=O)(=O)c1cccc2cccnc12

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.63
POLB P06746 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
QPCT Q16769 1/20 0.58
KMT2A Q03164 4/20 0.58
ALOX15 P16050 2/20 0.57
TSHR P16473 1/20 0.57
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HTR7 P34969 3/20 0.55
HTR6 P50406 1/20 0.53
HSD17B10 Q99714 1/20 0.52
FABP1 P07148 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7177153 0.92 PPARG (0.66) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL9239543 0.82 ALOX15 (0.71) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL14313616 0.82 ALOX15 (0.74) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL12085478 0.81 PPARG (0.62) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL30639808 0.81 PPARG (0.72) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL13949765 0.81 PPARG (0.72) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL2639089 0.79 PPARG (0.72) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL2639086 0.79 PPARG (0.72) PPARGPOLBSMN1; SMN2QPCTKMT2A
SCHEMBL7468069 0.79 PPARG (0.64) PPARGPOLBSMN1; SMN2KMT2AALOX15
SCHEMBL15850340 0.78 PPARG (0.80) PPARGPOLBSMN1; SMN2QPCTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists OY JUVANTIA PHARMA LTD. (FI) 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004339-A1 Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists SSTR4, SSTR1, SSTR3 PPARG 1628/4885POLB 4464/4885SMN1; SMN2 2541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.