Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137759 | 0.92 | PPARG (0.63) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL13949765 | 0.83 | PPARG (0.72) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL30639808 | 0.83 | PPARG (0.72) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL2639089 | 0.81 | PPARG (0.72) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL2639086 | 0.81 | PPARG (0.72) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL7468069 | 0.81 | PPARG (0.64) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL5622664 | 0.80 | SMN1; SMN2 (0.64) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL14313616 | 0.78 | ALOX15 (0.74) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL28590343 | 0.77 | PPARG (0.68) | PPARGPOLBSMN1; SMN2KMT2ATSHR | |
| SCHEMBL13949767 | 0.77 | POLB (0.68) | PPARGPOLBSMN1; SMN2KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-A2 | TREATMENT OF SEXUAL DYSFUNCTION | Warner-Lambert Company LLC (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002040008-A2 | TREATMENT OF SEXUAL DYSFUNCTION WITH NON PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | claimed |