Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729177 | 0.83 | USP30 (0.38) | DPP4 | |
| SCHEMBL12363784 | 0.69 | MEN1 (0.38) | KMT2A | |
| SCHEMBL13152927 | 0.68 | ALDH1A1 (0.33) | KMT2A | |
| SCHEMBL22864642 | 0.68 | PDE4B (0.39) | — | |
| SCHEMBL24729541 | 0.68 | PDE4B (0.39) | — | |
| SCHEMBL29801176 | 0.68 | PDE4B (0.39) | — | |
| SCHEMBL18373766 | 0.68 | ALDH1A1 (0.37) | KMT2A | |
| SCHEMBL13068139 | 0.68 | MEN1 (0.38) | KMT2A | |
| SCHEMBL31661168 | 0.65 | USP30 (0.41) | — | |
| SCHEMBL31147949 | 0.65 | HDAC2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555585-B | HPK1 inhibitors and uses thereof | 锐格药业公司 | 2025-02-11 | — | — | CN | disclosed |