Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 6/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14183129 | 0.85 | BCL2 (0.53) | BCL2GSK3BDYRK1AGRIN2BHDAC1 | |
| SCHEMBL3833158 | 0.81 | F10 (0.50) | BCL2GSK3BDYRK1AGRIN2BHDAC1 | |
| SCHEMBL5543076 | 0.81 | BCL2 (0.52) | BCL2GSK3BDYRK1AGRIN2BHDAC1 | |
| SCHEMBL16898754 | 0.81 | IRAK4 (0.46) | BCL2GSK3BDYRK1AGRIN2BBRS3 | |
| SCHEMBL27518744 | 0.79 | BCL2 (0.44) | BCL2GSK3BDYRK1AGRIN2BHDAC1 | |
| SCHEMBL23193793 | 0.78 | BCL2 (0.48) | BCL2GSK3BDYRK1AGAA | |
| SCHEMBL29627265 | 0.78 | BCL2 (0.48) | BCL2GSK3BDYRK1AGAA | |
| SCHEMBL12403311 | 0.78 | GSK3B (0.47) | BCL2GSK3BDYRK1AGRIN2BHDAC1 | |
| SCHEMBL29651977 | 0.77 | HCAR3 (0.57) | BCL2GRIN2BHDAC1 | |
| SCHEMBL2877186 | 0.77 | HCAR3 (0.57) | BCL2GRIN2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466844-B | N- (1H-imidazol-2-yl) benzamide compound and pharmaceutical composition comprising same as active ingredient | 康佳诺医疗科技发展有限公司 | 2025-02-18 | — | — | CN | disclosed |