Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | BTK | Q06187 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15393439 | 0.84 | LPL (0.41) | LPLLIPGCXCR2IDO1TDO2 | |
| SCHEMBL31378591 | 0.81 | LPL (0.39) | LPLLIPGCXCR2IDO1TDO2 | |
| SCHEMBL17752336 | 0.81 | LPL (0.39) | LPLLIPGCXCR2IDO1TDO2 | |
| SCHEMBL15392968 | 0.80 | LPL (0.38) | LPLLIPGCXCR2IDO1TDO2 | |
| SCHEMBL30508645 | 0.80 | LPL (0.38) | LPLLIPGCXCR2IDO1TDO2 | |
| SCHEMBL25426698 | 0.78 | LPL (0.36) | LPLLIPGCXCR2LIPEFFAR1 | |
| SCHEMBL30510470 | 0.78 | LPL (0.36) | LPLLIPGCXCR2LIPEFFAR1 | |
| SCHEMBL24587207 | 0.78 | LPL (0.36) | LPLLIPGCXCR2IDO1TDO2 | |
| SCHEMBL18865569 | 0.78 | LPL (0.36) | LPLLIPGCXCR2LIPEJAK2 | |
| SCHEMBL2453019 | 0.78 | LPL (0.36) | LPLLIPGCXCR2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020063965-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS SELECTIVE TRK INHIBITOR | 南京明德新药研发有限公司 | 2020-04-02 | — | — | WO | disclosed |