Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Mercaptopurine Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | MARK3 | P27448 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mercaptopurine Anhydrous SCHEMBL29684795 | 0.98 | LMNA (0.57) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL8844 | 0.98 | LMNA (0.57) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL5144254 | 0.96 | LMNA (0.55) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL30834915 | 0.96 | LMNA (0.55) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL734088 | 0.96 | LMNA (0.55) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL28474534 | 0.87 | HSD17B10 (0.50) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL1820743 | 0.82 | PI4KA (0.43) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL4447615 | 0.81 | MKNK1 (0.47) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Mercaptopurine Anhydrous SCHEMBL5534039 | 0.80 | ALDH1A1 (0.44) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29559610 | 0.76 | LMNA (0.57) | LMNAPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025013869-A1 | FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF | ダイキン工業株式会社 | 2025-01-16 | — | — | WO | disclosed |