Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SPR | P35270 | 2/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.57 |
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17739963 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBSPRTAS1R3 | |
| SCHEMBL19036929 | 0.94 | PDE2A (0.63) | ALDH1A1KDM4EPOLBSPRTAS1R3 | |
| SCHEMBL19579149 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL17743289 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL19555629 | 0.83 | KDM4E (0.59) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL19555656 | 0.80 | KDM4E (0.56) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL17743166 | 0.78 | KDM4E (0.58) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL17730266 | 0.78 | KDM4E (0.58) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL18357160 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 | |
| SCHEMBL17743195 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4ESPRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066364-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL R&D INVEST S A (PT) | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066364-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | PARK7, PNP, GAA | ALDH1A1 1213/4885KDM4E 899/4885POLB 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.