Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31024713 | 0.91 | PKM (0.40) | NR1H2PKMGPR183JAK2JAK1 | |
| SCHEMBL31738788 | 0.86 | NR1H2 (0.36) | NR1H2PKMALDH1A1 | |
| SCHEMBL31738786 | 0.79 | EED (0.34) | NR1H2PKMGPR183JAK2JAK1 | |
| SCHEMBL31738796 | 0.77 | PKM (0.40) | NR1H2PKMALDH1A1 | |
| SCHEMBL31738773 | 0.76 | PKM (0.42) | NR1H2PKMJAK2JAK1 | |
| SCHEMBL25342887 | 0.71 | PKM (0.42) | NR1H2PKMJAK2JAK1ALDH1A1 | |
| SCHEMBL31738799 | 0.71 | PKM (0.42) | NR1H2PKMJAK2JAK1ALDH1A1 | |
| SCHEMBL25342925 | 0.70 | EED (0.38) | NR1H2PKMGPR183JAK2JAK1 | |
| SCHEMBL25342550 | 0.70 | EED (0.38) | NR1H2PKMGPR183JAK2JAK1 | |
| SCHEMBL31738793 | 0.70 | EED (0.38) | NR1H2PKMGPR183JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4656642-A1 | ESTROGEN RECEPTOR PROTEOLYSIS TARGETING CHIMERA COMPOUND AND USE THEREOF | GAN & LEE PHARM CO., LTD (CN) | 2025-12-03 | — | — | EP | disclosed |
| WO-2025026283-A1 | COMPOUND FOR SELECTIVELY DEGRADING SMARCA2/4 AND USE THEREOF | 甘李药业股份有限公司 | 2025-02-06 | — | — | WO | disclosed |